Experts

Ke Yuebin

Brief Introduction

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Name

Yuebin Ke

Academic Title

ProfessorDeputy Director

Degree

Phd

Department

Key Laboratory of Medical Molecular Biology of Shenzhen

Correspondence Address

Shenzhen Center for Disease Control and Prevention, No 8. Longyuan Rd, Longzhu Blvd, Nanshan Dist, Shenzhen City 518055, P.R.China

Telephone

+86-755-25531876

E-mail

keyke@163.net

 

  Dr. Yuebin Ke is a professor of Shenzhen Center for Disease Control and Prevention. He is on the editorial board of the Chinese Journal of Preventive Medicine. He is also a member of the Chinese Preventive Medicine Society's Free Radical Preventive Medicine Committee, a PhD and Master's student adviser of the Huazhong Science and Technology University’s Tongji Medical College, an adjunct professor of life sciences at Shenzhen University, associate secretary-general of the Shenzhen Preventive Medicine Society, and associate director-member of the environmental health specialty committee. Ke graduated from Tongji Medical University in 1988 and from the Sun Yat-sen University in 1993. He is a visiting scholar of Hongkong University of Science and Technology and a senior visiting scientist of Virginia Polytechnic Institute and State University of USA.

  Ke's research is primarily in the areas of genetic toxicology and molecular biology. In recent years he has been charge of a number of scientific research projects including: Shenzhen Science and Technology Plan Key Project entitled "Research on the Effects of the Expression of the Gene for the DNA Oxidative Damage Repair Enzyme hOGG1" (200601020), Guangdong Provincial Natural Sciences Foundation Project entitled "Research on DNA Oxidative Damage Repair Mechanisms," Chinese National Natural Sciences Foundation Project entitled "Research on the Interaction between the DNA Oxidative Damage Repair Genes MTH1 and OGG1” (30872149C1504),and Chinese National Natural Sciences Foundation Project entitled "Research on the association between DNA oxidation and DNA methylation and their interactions" (81072323/ H2607). He has trained 10 PhD and Master's students during these research project.

Ke participated in the writing of a "Dictionary of Toxicology" (2005), was the deputy chief translator for "Field Epidemiology" (2005), and produced two monographs entitled "Potential Danger: Analysis of Misconceptions about Nutrition" (2008) and "Free Radical Toxicology"(2012). He has published 60 articles in international and domestic journals on research related to genetic toxicology and molecular biology. Ke was awarded the Shenzhen Municipal Science and Technology Innovation Award (2008) , Award of Science and Technology of Chinese Preventive Medicine Association (2009) and Award of Science and Technology of Chinese Medicine (2010).

 

Name: Yuebin Ke

Present position and title:

    ProfessorDeputy Director

    Key Laboratory of Medical Molecular Biology of Shenzhen

    Shenzhen Center for Disease Control and Prevention (Shenzhen CDC)

    PhD and Master's student adviser, School of Public Health, Tongji Medical College, Huazhong Science and Technology University

    Adjunct Professor, Academy of Life Sciences, Shenzhen University

Work Address:

No 8. Longyuan Rd, Longzhu Blvd, Nanshan Dist,

Shenzhen City 518055, P.R.China

Phone: +86 755 25531876  Fax+86 755 25531876

Email: keyke@szcdc.net   Netsite: http://192.168.156.38:9080

Education:

                                                           

Year      Degree     College or University            Field of study

                                                           

2012                 Virginia Polytechnic Institute     Molecular Biology

and State University

2009     D. Med.      Huazhong University of      

                    Science and Technology       Genetic Toxicology

1993     M. Med.     Sun Yat-Sen University       Genetic Toxicology

1988     B. Med.     Tongji Medical University      Environmental Medicine

                                                           

Employment:

                                                               

Period      Institution (Country)       Position               Discipline

                                                               

2004 to     Shenzhen CDC         Professor            Molecular Biology

present     (P.R.China)           (Prof. J Cheng)

          

2001 to     Shenzhen CDC       Associate Professor      Genetic Toxicology

2004       (P.R.China)           (Prof. Z Zhuang)               

                             

1997 to     Shenzhen CDC          Lecturer               Food Hygiene

2001         (P.R.China)          (Prof. Z Zhuang)           and Epidemiology

          

1993 to     Shenzhen CDC          Physician           Occupational Health

1997       (P.R.China)           (Prof. T Wang)           

                                                               

Professional Organizations:

1.   Editor of Chinese Journal of Preventive Medicine

2.   Councillor of Chinese Free Radicals Medicine Society

3.   Member of Chinese Environmental Mutagen Society

4.   Associate secretary-general of the Shenzhen Preventive Medicine Society

5.   Associate director-member of the environmental health specialty of SPMS

6.   Reviewer for Public Health Nutrition, England

7.   Evaluation experts of National Natural Science Foundation of China

Awards and Honors:

1.  Award of Science and Technology of Chinese Medicine, 2010

2.  Award of Science and Technology of Chinese Preventive Medicine Association, 2009

3.  Shenzhen Municipal Science and Technology Innovation Award, 2008

4.  Top Ten research and teaching workers of Shenzhen health system,2011

5.  Award of Shenzhen Municipal People's Government, 2003

Research Supports:

Ongoing Research Support

Chinese National Natural Sciences Foundation ProjectResearch on the association between DNA oxidation and DNA methylation and their interactions (81072323/ H2607)              NSFC Total Cost: RMB 320000  Principal Investigator: Y. Ke  01/01/2011-12/31/2013

Completed Research Support

1Chinese National Natural Sciences Foundation ProjectResearch on the Interaction between the DNA Oxidative Damage Repair Genes MTH1 and OGG1 (30872149C1504)              NSFC Total Cost: RMB 300000  Principal Investigator: Y. Ke  01/01/2009-12/31/2011

2Guangdong Provincial Natural Sciences Foundation ProjectResearch on Repair Mechanisms of Oxidative DNA Damage (8451802003000336)

NSFG Total Cost: RMB 150000  Principal Investigator: Y. Ke  01/01/2008-12/31/2010

3Shenzhen Science and Technology Plan Key ProjectResearch on the Effects of Immigration on the Expression of hOGG1 (200601020)

SSTP Total Cost: RMB 180000  Principal Investigator: Y. Ke  01/01/2006-12/31/2009


Recent Publications:

1.     Ke Y*, Cheng J, Zhang Z, Zhang R, Zhang Z, Shuai Z, Wu T. Increased levels of oxidative DNA damage attributable to cooking oil fumes exposure among cooks. Inhalation Toxicology, 2009,21(8):682-687.

2.     Ke Y*, Zhang Z, Jiang Y, Zhuang Z, Li L, Lu W, Wu T. Association of hOGG1 genotype with life style and oxidative DNA damage among Chinese ethnic populations. Arch Toxicol. 2009,83(7):663-668.

3.     Xu X, Yang R, Ke Y, Zhou L, Yuan J, LI G, Huang H, Wu W. Severe hypersensitivity dermatitis and liver dysfunction induced by occupational exposure to trichloroethylene. Ind Health. 2009, 47(2):107-12..

4.  Ke Y*, Duan X, Wen F, Xu X, Tao G, Zhou L, Zhang R, Qiu B. Association of melamine exposure with urinary stone and oxidative DNA damage in infants. Arch Toxicol. 2010, 84(4):301–307.

5.     Xu X, Wu P, Ke Y, Zhou L, Yuan J, Huang H. Oxidative stress and inducible nitric oxide synthase expression in human hepatocytes treated with trichloroethylene. Toxicological & Environmental Chemistry. 2010, 92(4):801-811.

6.     Ke Y*. Effects of potassium bromate on the expression of hOGG1 mRNA in human bronchial epithelial cell lines. Free Radic Biol Med. Dol: 10.1016/j.freeradbiomed.2010.10.472.

7.     Li L, Zhou Y, Wang GF, Liao SC, Ke YB, Wu W, Li XH, Zhang RL, Fu YC. Anaphase-promoting complex/cyclosome controls HEC1 stability. Cell Prolif.2011,44(1),1-9.

8.     Xu XY, Liu YF, Lu LW, Ke YB, Mao JY, Mao KL. Altered expression of hepatic metabolic enzyme and apoptosis-related gene transcripts in human hepatocytes treated with trichloroethylene. Hum Exp Toxicol.2012,31(9):861-7

9.     Ke Y*, Xu X, Wu S, Huang J, Geng Y, Misra H, Li Y. Protective Effects of Extracts from Fructus rhodomyrti against Oxidative DNA Damage In Vitro and In Vivo. Oxidative Medicine and Cellular Longevity. http://dx.doi.org/10.1155/2013/507407.

10.   Zhang Y, Tong Y, Zhang Y, Ding H, Zhang H, Geng Y, Zhang R, Ke Y, Han J, Yan Z, Zhou L, Wu T, Hu FB, Wang D, Cheng J. Two Novel Susceptibility SNPs for Ischemic Stroke Using Exome Sequencing in Chinese Han Population. Mol Neurobiol. Dol 10.1007/sl2013-013-8561-0.